CAFFEINE CITRATE

Brand Name & Strength

Cafnea™ Injection 40 mg/2 ml (equivalent to caffeine 20 mg/2 ml)

Reconstitution

Not required

Further Dilution

Undiluted or dilute with diluent to a concentration of 10 mg/ml

Diluent

D5

Administration & Infusion rate

IV infusion

(by syringe infusion pump)

Loading dose: Administer over 30 min

Maintenance dose: Administer over 10 min

Storage & Stability

RT

(<25 oC)

Fridge

(2-8 oC)

After Reconstitution

- -

After dilution

24 hr -

Remarks

Stable for 24 hours at room temperature when combined with:

D5;

Intralipid® 20% IV fat emulsion;

Aminosyn® 8.5% crystalline amino acid solution;

Dopamine hydrochloride injection 40 mg/ml diluted to 0.6 mg/ml with D5;

Calcium gluconate injection 10% (0.465 mEq/ml Ca2+);

Heparin sodium injection 1,000 units/ml diluted to 1 unit/ml with D5;

Fentanyl citrate injection 50 mcg/ml diluted to 10 mcg/ml with D5